NFL Week 5 takeaways - Lessons, big questions for every game

Week 5 of the 2022 NFL season kicked off Thursday night with an Indianapolis Colts victory at the Denver Broncos that went into overtime. Usually extra action means lots of big offensive plays, but somehow neither team managed to score a touchdown in the 12-9 affair.

For the second week in a row, we got some Sunday morning action, as the New York Giants faced the Green Bay Packers in London, England. This game came right down to the wire, as the Giants held off the Packers for a 27-22 victory.

Our NFL Nation reporters react with the biggest takeaways and lingering questions coming out of this week's matchups and look ahead to what's next. Let's get to it.

Jump to a matchup:

IND-DEN | NYG-GB

What to know: Daniel Jones and the Giants really showed something. They rallied from down 14 in the first half against the Packers to post a huge upset victory, perhaps their best win since beating the Cowboys late in 2016. Jones did it while clearly not 100% (ankle) and despite a questionable supporting cast. If anything, it put his toughness on full display. Jones went 13-of-14 passing for 136 yards in the second half. He also rushed seven times for 37 yards, before kneeling with the ball late. Jones carried a Giants offense that had Marcus Johnson, Richie James, David Sills V and Darius Slayton at wide receiver. A monster effort.

How did star RB Saquon Barkley come out of the game? The Giants' offense revolves around Barkley. He accounted for 43% of their total offense coming into the game and said this week he's «good with whatever [workload] they throw at me.» But after New York went to Barkley early and often, he left Sunday's contest in the third quarter with a shoulder injury. He went to the locker room before returning to