The Dragons welcome the Ospreys to Rodney Parade this afternoon, with both teams searching for their second victory of the season.
The Ospreys are without Stephen Myler but fit-again Wales flanker Justin Tipuric returns on the bench.
Wales prop Gareth Thomas also returns, with wing Luke Morgan and fly-half Jack Walsh the other starting changes to the side that drew with the Stormers last weekend.
The home side make six changes from the side beaten 31-14 at Cardiff, including the return of Aaron Wainwright.
Also coming in are Jordan Williams, Steff Hughes, Gonzalo Bertranou, Harrison Keddie and Wales call-up Rhodri Jones.
Kick-off is at 3pm and you can follow all the action from throughout the day in the live blog below.
Dragons RFC: Jordan Williams; Rio Dyer, Steff Hughes, Jack Dixon, Jared Rosser; JJ Hanrahan, Gonzalo Bertranou; Rhodri Jones, Bradley Roberts, Lloyd Fairbrother, Ben Carter, Will Rowlands (capt), Aaron Wainwright, Harrison Keddie, Ross Moriarty.
Replacements: Elliot Dee, Aki Seiuli, Chris Coleman, Joe Davies, Sean Lonsdale, Rhodri Williams, Sam Davies, Max Clark.
Ospreys : Max Nagy; George North, Owen Watkin, Michael Collins, Luke Morgan; Jack Walsh, Rhys Webb (capt); Gareth Thomas, Dewi Lake, Tomas Fancis, Adam Beard, Alun Wyn Jones, Ethan Roots, Jac Morgan, Morgan Morris.
Replacements : Scott Baldwin, Nicky Smith, Tom Botha, Rhys Davies, Dan Lydiate, Justin Tipuric, Reuben Morgan-Williams, Joe Hawkins.
Alun Wyn Jones
Adam Beard
Dewi Lake
Dan Lydiate
Justin Tipuric
George North
Jac Morgan
Michael Collins
Elliot Dee
Aaron Wainwright
Joe Hawkins
Rhys Webb
Owen Watkin
Gareth Thomas
Will Rowlands
Nicky Smith
Gonzalo Bertranou
Rhys Davies