NFL Week 4 injury report: Updates on Jaire Alexander, Keenan Allen and others

Week 4 of the NFL season is here, and teams continue to assess injuries to their players ahead of game time.

The San Francisco 49ers have suffered another blow to their offense, as star left tackle Trent Williams is expected to be out four to six weeks with an ankle injury. Linebacker Azeez Al-Shaair will miss time after he sprained an MCL against the Denver Broncos. The New York Giants also lost a key offensive player after wide receiver Sterling Shepard tore an ACL against the Dallas Cowboys on Monday, ending his season.

The New England Patriots will be without quarterback Mac Jones, who suffered a high ankle sprain last week against the Baltimore Ravens. Veteran Brian Hoyer will start Sunday against the Green Bay Packers. He has lost 11 consecutive starts.

In more positive news, New York Jets quarterback Zach Wilson is expected to make his 2022 debut against the Pittsburgh Steelers on Sunday. Wilson has been out since the first game of the preseason because of a torn meniscus and a bone bruise in his right knee.

Our NFL Nation reporters have more updates on key players entering the weekend:

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Injury: Knee

Patterson is officially listed as questionable on the team's injury report, but he told ESPN on Friday that he plans on playing against the Cleveland Browns.

«I feel like I'm going to play every Sunday, no matter what the situation is,» Patterson said. «I plan on playing Sunday and we all know that's the plan.»

Patterson, the NFL's third-leading rusher, did not practice Wednesday or Thursday and was listed as a «resting player/knee.» He returned to practice Friday, did work on a limited basis and then was listed as questionable with a knee injury.

Coach Arthur Smith said