Pep Guardiola is not expecting any Manchester City players to return from injury against Southampton and is in the dark about Kevin De Bruyne's problem.
De Bruyne has not played since being taken off in the Champions League game against Inter Milan in September with a thigh issue.
While he returned to training last week, Guardiola has said the player still needs to feel 100 per cent fit and as of Friday the manager has no clue when that will be.
It means City will be without six players for the home game against Southampton. On top of De Bruyne, they are missing Rodri, Oscar Bobb, Jack Grealish, Jeremy Doku and Kyle Walker. ALSO READ: Begiristain transfer stance to be tested one more time after Man City bombshell ALSO READ: 'Want to address it' Kyle Walker clears the air over Man City mistake City will still be heavy favourites against a Southampton side that are struggling at the bottom of the Premier League, although Guardiola backed the stance of manager Russell Martin to stick to his principles.