Former Manchester United midfielder Paul Scholes admitted Casemiro was a "big loss" for the Reds as Erik ten Hag's side lost away at Newcastle.
The Brazilian midfielder was absent as he continues to serve a four-match ban after being sent off in the goalless draw with Southampton last month.
He will be sidelined for the next two domestic matches, which is a blow for United given how disappointing they were against Newcastle on Sunday.
Eddie Howe's side secured a 2-0 victory over United at St. James' Park, with Joe Willock and Callum Wilson both on the scoresheet for the home side.
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