Manchester United take on Sevilla at Old Trafford in the first leg of the Europa League quarter-final on Thursday night. United have already defeated Barcelona and Real Betis, who are above Sevilla in the La Liga table, in the Europa League this season and they are heavy favourites to win the competition for the second time since it was rebranded.
Sevilla have struggled this term and they sit in the bottom half of La Liga. They recently sacked Jorge Sampaoli and Jose Luis Mendilibar, who has managed multiple teams in Spain throughout his career, has taken charge.
Regarding the early team news, Casemiro is available for selection, but Marcus Rashford, who has scored 28 goals this season, sustained an injury against Everton last weekend and is out through injury, just like Luke Shaw.
Shaw was brought off in the first half in the recent win against Brentford and has been sidelined since. Follow below for live updates from Old Trafford. Erik ten Hag is optimistic Marcus Rashford will make a swift return from his apparent groin injury.