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Betting tips for Thursday Night Football: Rams vs. Bills

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The NFL season kicks off Thursday night with the defending Super Bowl champion Los Angeles Rams hosting the Buffalo Bills at SoFi Stadium in Inglewood, California.

Sure, we're all excited to watch real, meaningful games again, but we also have the opportunity to wager on them if we so choose.

So what plays to our analysts like in the season's first game? Betting analysts Doug Kezirian, Tyler Fulghum, Joe Fortenbaugh, Anita Marks and Erin Dolan; fantasy and sports betting analysts Eric Moody and Andre Snellings; ESPN Stats & Information'sSeth Walder, ESPN analystJason Fitz and Football Outsiders'Aaron Schatz provide their top plays for the opener.

Note: Lines from Caesars Sportsbook unless otherwise indicated. Joe Fortenbaugh: I think this game is a 50-50 proposition, which means I'll take the 2.5 points with the defending champs.

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Week 2 of the NFL season commenced with the Kansas City Chiefs defending home turf against the AFC West division rival Los Angeles Chargers in a 27-24 win. What will Sunday's slate hold for bettors? Our crew explores the biggest storylines, key matchups, which teams will or won't bounce back and offer their favorite plays and props. And don't forget, we'll have more to come on the Monday Night Football doubleheader this week with Titans-Bills on ESPN/ESPN2 at 7:15 p.m. ET and Vikings-Eagles at 8:30 p.m. ET on ABC/ESPN+.
Week 2 of the NFL season kicks off Thursday night with an AFC West clash between the Los Angeles Chargers and Kansas City Chiefs (-4, 54.5) at GEHA Field at Arrowhead Stadium. With the season now in full swing, there are plenty of opportunities to wager on the game if you so choose. So what plays do our analysts like in a matchup of Super Bowl hopefuls?

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