Real Madrid striker Kylian Mbappe will hope to build on from his brace against Real Betis before the international break. Los Blancos travel to San Sebastian on Saturday to face Real Sociedad, having drawn two of their first four matches, yet to fire on all cylinders.
Hansi Flick's Barcelona face Girona on Sunday in a Catalan derby aiming to secure a fifth win from five La Liga matches at the start of the season.
Last season the Catalan giants were upset twice by their upstart minnow neighbours, who thumped Xavi Hernandez's side 4-2 home and away in the top flight.
Girona, in their fourth ever season in La Liga, ultimately finished third, behind second-place Barca, but for much of the season the Blaugrana could only watch as the tiny club battled Real Madrid for top spot.