Woman who 'smelled disease' on husband inspires scientists to develop three-minute test for Parkinson's

A retired nurse who discovered she could 'smell Parkinson's disease' has inspired scientists to develop a test which could be used to diagnose it. Researchers at the University of Manchester hope the new method, which uses skin swabs, could diagnose the disease in just three minutes.

They were inspired by Joy Milne, who found she had the ability to smell Parkinson's when her husband Les was diagnosed aged 45. Joy, 72, says she noticed a change in the way he smelled and linked it to the 'musky' odour of other people they met at a Parkinson's UK support group. Les died in June 2015.

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Joy, of Perth in Scotland, said: " It dawned on me that every person with Parkinson's that I met had the same unique, musky odour as Les and I realised it was the condition itself I could smell. I was surprised that no-one had made the connection before - but when I mentioned it to a researcher from the University of Edinburgh he was intrigued."

A test whereby Joy, who has hereditary Hyperosmia – a heightened sensitivity to smells, had to sniff t-shirts worn by people with and without Parkinson's was set up. She got all bar one correct.

Scientists at the University of Manchester, working with Joy, have now developed a skin-swab which they say is 95pc accurate under laboratory conditions when it comes to telling whether people have Parkinson's. They collected sebum - the oily substance on skin - from patients' backs and compared 79 people with Parkinson's with 71 people without the disease.

Of the more than 4,000 unique compounds in the sebum, 500 were found to be different in people with Parkinson's. There is currently