Top seed Daniil Medvedev beaten by Nick Kyrgios at US Open

By George Ramsay, CNN

Updated 0924 GMT (1724 HKT) September 5, 2022

Medvedev was ousted in four sets by Nick Kyrgios at the US Open.

(CNN)Defending champion Daniil Medvedev was knocked out of the US Open after losing 6-7 6-3 3-6 2-6 against Nick Kyrgios in the fourth round.

Medvedev won his first grand slam title in New York last year, but on Sunday was bettered by Kyrgios, who is enjoying the best run of results in his career — reaching the Wimbledon final in July and winning the Citi Open title in Washington last month.The result means Medvedev will cede his position at the top of the world rankings come the end of the tournament, while Kyrgios will appear in his first US Open quarterfinal when he faces another Russian playing under a neutral flag, Karen Khachanov, on Tuesday. Medvedev later said he had struggled physically on the court, but added that Kyrgios outplayed him in the last two sets. «Today, I felt a little bit sick,» he told reporters after the match. «The thing is in the USA I get sick one time for sure in the swing because the AC (air conditioning) is just crazy. Last year it happened in Cincinnati.»Read More«I felt my throat a little bit today… At the same time, it's not an excuse at all because Nick played good.»Kyrgios celebrates against Medvedev — his fourth win against the world No. 1 in five encounters. It was the fourth time Kyrgios had beaten Medvedev in five meetings and the second time in as many months after victory in Montreal. The Australian saved several set points in a close first-set tie break — the first set Medvedev had dropped in the tournament — before falling behind in the second set when he dropped serve twice. Medvedev leveled the match, but momentum swung in Kyrgios' favor when he