Ross Byrne starts for Ireland as six changes made for Italy clash

Ross Byrne and Craig Casey will make their first starts in the Six Nations for Ireland as they make six changes for their clash against Italy.

Byrne replaces the injured Johnny Sexton, with second row James Ryan named as captain in his absence.

Iain Henderson joins Ryan in the second row in his first start in this season's tournament, with Jack Conan also coming into the side at number eight.

Calen Doris moves to flanker, with Josh Van Der Flier at number seven.

Our line up for Rome!