Pat McAfee pokes fun at Anthony Fauci pleading the Fifth Amendment live on ESPN

Philadelphia Eagles defensive coordinator Vic Fangio jokingly invoked the Fifth Amendment during a team press conference following Anthony Fauci's Senate hearing.

Pat McAfee has become ESPN's most powerful and influential personality. That's why he enjoys so much autonomy, commands one of the network's richest contracts and can say or do things on his "progrum" that other ESPN personalities wouldn't dream of attempting — or wouldn't be allowed to get away with.

During Thursday’s show, McAfee poked fun at Dr. Anthony Fauci, who pleaded the 5th Amendment a reported 111 times while "speaking" at the United States Senate hearing.

Pat McAfee appears on the College GameDay show before a game between the Tennessee Volunteers and the Georgia Bulldogs at Neyland Stadium in Knoxville, Tenn., on Sept. 13, 2025. (ISI Photos via Getty Images)

During a parody segment in which he pretended to interview Eagles defensive coordinator Vic Fangio live, McAfee asked, "Vic, we appreciate you joining us. Do you think your team will win the Super Bowl this year?"

EAGLES COACH VIC FANGIO MOCKS ANTHONY FAUCI'S SENATE HEARING SPECTACLE DURING HIS OWN PRESS CONFERENCE

Fangio’s answer was a replay of his earlier press conference at Eagles’ camp where he jokingly responded to reporter’s questions by stating, "I’m gonna be like Fauci, and just take the 5th Amendment on all your questions."

They did this back and forth song and dance with multiple "Pat McAfee Show" personalities asking him questions about Jalen Carter getting a massive extension, splicing in Fangio pleading the 5th.

Feb 5, 2025; New Orleans, LA, USA; Philadelphia Eagles defensive coordinator Vic Fangio speaks with the media during a press conference at Hilton New Orleans Riverside.