Novak Djokovic 'happy with performance' as Andy Murray exits Wimbledon to John Isner

Defending champion Novak Djokovic declared himself "happy with my performance" after cruising into the third round at Wimbledon as career-long rival Andy Murray suffered his earliest-ever exit from the All England Club.

Top seed Djokovic brushed aside Australia's Kokkinakis 6-1, 6-4, 6-2 and will next face Serbian compatriot Miomir Kecmanovic.

"I'm very happy with my performance. I started very well, solid from the back of the court," said Djokovic, who is looking to join Pete Sampras as a seven-time Wimbledon champion.

"I made him work for every point and worked him around the court," added the 20-time major winner.

Murray, now 52 in the rankings, failed to break serve once against 2018 semi-finalist Isner, who unleashed 36 aces and 82 winners in total.

"He didn't give me lots of chances," said Murray, whose previous earliest exits came in the third round in 2005 and 2021.

"My game was in a good place. I felt good on the court, just couldn't get the win."

Isner, 37, was gracious in the aftermath of his first win in nine meetings against the Briton.

"I am most definitely not a better tennis player than Andy Murray. I might have been a little bit better than him today," said the American.

Isner also took his career aces total to 13,724 to sit just four behind the record held by Ivo Karlovic.

John Isner of the United States, right, consoles Andy Murray of Great Britain after winning their second-round match at Wimbledon 2022. Getty Images

Third seed and French Open runner-up Casper Ruud, who was scheduled to face Djokovic in the semi-finals, was knocked out by 112th-ranked Ugo Humbert, 3-6, 6-2, 7-5, 6-4.

But Spanish teenager Carlos Alcaraz stayed on course to meet the six-time champion in the last eight by reaching the