NFL schedule 2022 winners, best matchups, must-watch debuts, Super Bowl and win total predictions -- Experts make their picks

The 2022 NFL schedule is out, and the league enters its second year with 17 regular-season games after playing a 16-game schedule since 1978. The regular season kicks off on Thursday, September 8, with the Buffalo Bills visiting the Super Bowl champion Los Angeles Rams. Week 1 also features Russell Wilson's return to Seattle on Monday Night Football, Tom Brady in Dallas, Patrick Mahomes vs. Kyler Murray and six in-division matchups.

Other highlights for the 2022 slate include a Super Bowl LV rematch between the Kansas City Chiefs and Tampa Bay Buccaneers (Oct. 2), an offensive duel between Aaron Rodgers and Josh Allen (Oct. 30) and and a late-season Battle of Los Angeles (Jan. 1, 2023). There are also five international contests, including the league's first game in Germany (Buccaneers vs. Seattle Seahawks on Nov. 13) and a return to Mexico City (Arizona Cardinals vs. San Francisco 49ers on Nov. 21). One of three London games will feature the Green Bay Packers — the lone NFL team yet to play internationally.

What should we make of the 2022 slate? Who's the biggest winner from the schedule release? Which games should you circle on your calendar? Which debut will be the most interesting, and which late-season matchup could prove important for the postseason? Our panel of NFL experts weighs in on all that and more, including predictions for this season's Super Bowl.

Skip to a question:

Which matchup do you have circled on your calendar?

Who or what is the biggest winner of the schedule release?

Which debut are you most interested in, and why?

Which win total over or under do you feel best about picking right now?

Which late-season matchup will have playoff implications?

What's your early Super Bowl pick?

Sarah Barshop, Rams