Men's March Madness 2025: Best bets for the round of 32 - ESPN

The 2025 men's NCAA tournament continues Sunday with the second day of the Round of 32, and that presents several excellent betting opportunities. The tournament has been full of exciting games and close finishes, including two No. 12 seeds punching their tickets to the second round, and players like Mark Sears and Sean Pedulla stepping up for their squads.

So what can we expect on Sunday, and which point spreads and over/unders are worth betting on?

Here is Greg Peterson to factor in team trends, injuries, momentum and more to identify the smartest wagers to make over the weekend.

Odds are accurate as of publication time. For the latest odds, go to ESPN BET.

No. 1 Florida vs. No. 8 UConn, 12:10 p.m. ET
Bet: Under 151.5

UConn is one of the slowest paced teams remaining in the field and the underwhelming full-season numbers on defense are not indicative of how the team is currently playing, allowing 71 points or fewer in 10 of its past 12 games. UConn also leads the country in block shot percentage with three separate players — Samson Johnson, Alex Karaban and Tarris Reed Jr. — all averaging at least 1.5 blocks per game. Florida is one of the few teams that can match that size with six different players averaging at least 4.5 rebounds per game, with Alex Condon's 7.9 rebounds per game leading the way. With Florida a top 15 team in opponent 2-point and 3-point shooting percentage, points will be at a premium.

No. 2 Alabama vs. No. 7 Saint Mary's, 6:10 p.m. ET
Bet: Saint Mary's +5.5

This is a classic tempo war, with Saint Mary's playing at one of the slowest paces in all of college basketball and Alabama playing at one of the fastest. It's very off-putting that Alabama has allowed 79 points or more in 10 of its past 12