Men's March Madness 2025: Best bets for the Elite 8 - ESPN

The 2025 men's NCAA tournament continues Saturday and Sunday with the Elite 8 and things are only getting more exciting.

So which point spreads and over/unders are worth betting on? And what else stands out from a bettor's perspective?

Let's factor in team trends, injuries, momentum and more to identify the smartest wagers to make over the weekend.

Odds are accurate as of publication time. For the latest odds, go to ESPN BET.

No. 1 Florida Gators vs. No. 3 Texas Tech Red Raiders, 6:09 p.m. ET
Bet: Under 156.5

Texas Tech came back from down 13 points against Arkansas with less than five minutes remaining in regulation, winning an instant classic in overtime, which may leave them with less in the tank for Saturday. The Red Raiders were also without Chance McMillian again on Thursday, who is their top 3-point shooter, averaging 14.2 points per game on 43.4% 3-point shooting this season. He is expected to either be out again on Saturday or quite limited. Florida is not allowing any clean looks, ranking 15th in opponent 2-point shooting percentage and fifth in opponent 3-point shooting percentage. With Texas Tech's rotation thin due to the McMillian injury, it should lead to a slower game and fewer scoring opportunities.

No. 1 Duke Blue Devils vs. No. 2 Alabama Crimson Tide, 8:49 p.m. ET
Bet: Under 174.5

While Alabama leads the country in total possessions per game, Duke entered the Sweet 16 ranked No. 280 in possessions per game and third in the country in points per possession allowed. Alabama's 25 made 3-point shots on Thursday were the most in tournament history with Mark Sears going 10-of-16 from long range after shooting a cool 5-of-35 on 3-point shots in the previous six games. With Duke ranked 36th in the nation