Falcons' Marcus Mariota scores 3 touchdowns as Atlanta upends 49ers

Fox News Flash top headlines are here. Check out what's clicking on Foxnews.com.

Marcus Mariota threw a pair of touchdown passes and ran for another score against the NFL's top-ranked defense, leading the Atlanta Falcons to a 28-14 victory over the San Francisco 49ers on Sunday.

Mariota completed his first 13 passes for the Falcons (3-3), finally throwing his lone incompletion on his final attempt of the day with less than 11 minutes remaining. He finished with 129 yards through the air in Atlanta's conservative passing game, also rushing for 50 yards on six carries.

CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COM

Atlanta Falcons quarterback Marcus Mariota (1) runs against the San Francisco 49ers during the second half of an NFL football game, Sunday, Oct. 16, 2022, in Atlanta.  (AP Photo/John Bazemore)

The Niners (3-3) couldn't overcome two interceptions by Jimmy Garoppolo and a fumble that was returned for a touchdown by the Falcons.

Kyle Pitts caught his first TD pass of the season and just the second of his 22-game career, hauling in a 7-yard throw from Mariota that prompted the young tight end to break out the vintage "Dirty Bird" dance.

Veteran tight end MyCole Pruitt, who was elevated from the practice squad for the game, collected the other scoring pass from Mariota, a 2-yarder to cap an 11-play, 74-yard drive on Atlanta's opening possession.

Mariota bootlegged it in from the 3 in the final minute of the first half to the put the Falcons ahead to stay, 21-14.

TUA TAGOVAILOA CLEARS CONCUSSION PROTOCOL, EYES POTENTIAL WEEK 7 RETURN: REPORTS

San Francisco 49ers quarterback Jimmy Garoppolo (10) is stripped of the ball by Atlanta Falcons defensive end Grady Jarrett (97) and San Francisco 49ers guard Aaron Banks