England vs Wales LIVE: Six Nations rugby score and latest updates as Marcus Smith kicks hosts in front

LIVE – Updated at 17:35

Follow live coverage as England host Wales in a crunch Six Nations match at Twickenham on Saturday evening.

Defeat to Scotland in the opener at Murrayfield leaves little margin for error for today’s hosts and coach Eddie Jones knows nothing less than a win will do with tournament favourites Ireland and France still to come. They will have to do it without Manu Tuilagi, however, with the Sale centre recalled only to later be ruled out by injury. Back row Courtney Lawes is back though and will captain the side while Ben Youngs must surpass Jason Leonard’s record as England’s most capped player as a replacement with Harry Randall continuing as starting scrum-half.

For Wales, Louis Rees-Zammit is the surprise omission with fit-again Josh Adams and Alex Cuthbert preferred on the wings. Number eight Taulupe Faletau will makes his first international appearance for 11 months, having successfully proved his fitness following a long-term ankle injury.

Follow all the latest updates and analysis:

George throws the line-out and Itoje catches. The hosts look to create a maul to charge over but Wales do enough to smother the ball and win the penalty. Cracking job for Wales with returning Falatau getting that one.

Now it’s a Wales line-out and it’s clean as the visitors look to get some points on the board. Tomos Williams box kicks and Nowell collects - the ball exchanging hands so quickly.

Smith kicks away and L Williams catches, slow ruck ball from Wales is silencing any attack they’ll want. Wales kick away and England now have it, this game needs an injection of something with both defences holding strong so far!

England have a penalty advantage for a Welsh error on the floor.

Wales were getting into their