Cursed: All four of the Arizona Cardinals first four draft picks are injured, with two out for the season

Arizona Cardinals rookie running back Jeremiyah Love sustained an ankle injury in the team's first preseason game and will be out for at least a week. (This video contains AI-assisted content)

The Arizona Cardinals are in rebuild mode (again), with a new head coach and a quiver of promising draft picks, but their roster reconstruction has gone sideways mere weeks into the start of training camp because their top four rookies are all injured.

Arizona's first round pick is injured.

The second round pick is out for the season.

The third round pick is injured.

The fourth round pick is out for the season.

The Cardinals had seven selections in the April NFL draft. A majority are injured.

The Cursedinals.

Arizona Cardinals running back Jeremiyah Love spins away from Las Vegas Raiders cornerback Hezekiah Masses during the first half of a preseason NFL football game Thursday, Aug. 13, 2026, in Las Vegas. (AP Photo/David Becker)

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The latest of the bad news is that running back Jeremiyah Love, the third player taken in the first round of the draft, is out indefinitely with an ankle injury. And, this isn't just a tweak.

Love is likely to miss the remainder of the preseason and his availability for the start of the season is in question.

That news comes hours after head coach Mike LaFleur announced that guard Chase Bisontis, the team's second round pick and the 34th player taken in the draft, is going to miss the entire season.

Arizona Cardinals head coach Mike LaFleur speaks during a press conference after the first round of the NFL Draft at the team's facility in Tempe, Arizona, on April 23, 2026. (Joe Rondone/The Republic