The reigning Formula E champion looked imperious in the lead, having wrested control of the race as early as the first corner from Mortara with a surprise launch down the inside from third on the grid.
Mortara, who was perhaps preoccupied with trying to defend from fellow front-row starter Robin Frijns, left a smidgen of space on the inside of the corner which de Vries took with glee, scooping up the lead and immediately beginning to build a break over the Mercedes-powered Venturi.
De Vries then took the initiative with his attack mode activation - this time, a solitary attack mode spanning eight minutes - and briefly conceded the lead back to Mortara by picking up the 250kW power mode on lap 9, but re-passed two laps later into the first corner once more.
From there, the Dutchman rarely looked threatened, although Mortara tried a slightly different attack mode strategy to try and resolve his first-corner disappointment and catch back up to de Vries.
Waiting for the other frontrunners to run out of attack mode, a strategy which worked for his victory on Saturday, Mortara hung on until lap 15 - six laps later than de Vries, Antonio Felix da Costa and Stoffel Vandoorne - to enter the realm of 250kW power.
With the incentive to start making moves through the field after dropping to fifth, Mortara cleared Andre Lotterer, Vandoorne and da Costa on consecutive laps to return to second, setting about eating into de Vries' lead.
But Mortara couldn't quite contend with de Vries' pace and energy, where the gap remained at around 2.5s throughout the second half of the race as the Mercedes driver had the race in the palm of his hand.
Thus, de Vries collected his first win since the Diriyah season opener, 2.454s clear of Mortara -
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