2024 NFL Week 5 betting: New Orleans Saints vs. Kansas City Chiefs odds, picks, lines - ESPN

Week 5 of the NFL season concludes with a «Monday Night Football» matchup featuring Patrick Mahomes' 4-0 Kansas City Chiefs, who are looking to keep pace with the Minnesota Vikings as the only two undefeated teams in the league, hosting Derek Carr, Alvin Kamara and the New Orleans Saints (2-2), who are looking to get back to their winning ways after dropping two in a row. The line for the game opened at -5 at ESPN BET and hasn't moved since with a current total of 43.5 points.

Betting analyst Seth Walder gives his favorite bet for Saints-Chiefs, and you'll also find betting trends provided by ESPN Research.

Odds current as of publish time. For the most up-to-date lines, go to ESPN BET

Spread: Chiefs (-5)
Money line: Chiefs (-240), Saints (+200)
Over/Under: 43.5

First-half spread: Chiefs -3.5 (Even), Saints +3.5 (-130)
First-half money line: Chiefs (-190), Saints (+150)
Chiefs total points: O/U 23.5 (-125/-105)
Saints total points: O/U 18.5(-125/-105)

Patrick Mahomes total passing yards: O/U: 224.5 yards (-140/+110)
Derek Carr total passing yards: O/U: 199.5 yards (-145, +115)
Mahomes total passing TDs: O/U: 1.5 TDs (-115/-115)

Alvin Kamara total rushing yards: O/U 69.5 (+110/-140)
Kareem Hunt total rushing yards: O/U 44.5 (-105/-125)
Mahomes total rushing yards: O/U 19.5 (+105/-135)

Travis Kelce total receiving yards: O/U 59.5 (-115/-125)
Rashid Shaheed total receiving yards: O/U 49.5 (-105/-125)
Chris Olave total receiving yards: O/U 59.5 (-115/-125)
Xavier Worthy total receiving yards: O/U 44.5 (Even/-130)
Kamara total receiving yards: O/U 34.5 (-105/-125)
Justin Watson total receiving yards: O/U 24.5 (-120/-110)
Noah Gray total receiving yards: O/U 29.5 (-130/Even)
Juwan Johnson total receiving yards: O/U 14.5 (+110/-140)
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