Erik ten Hag is likely to ring the changes as he approaches his maiden European night in charge of Manchester United. After a slow start, the Dutchman's reign has kicked into gear with four successive Premier League wins.
Attentions now turn to the Europa League, with Spanish side Real Sociedad visiting Old Trafford on Thursday night. It represents the first of six group games that are being shoehorned into a smaller window, owing to the winter World Cup.
Despite being reluctant to make too many alterations to a winning side, Ten Hag is expected to rotate for the visit of Imanol Alguacil's side.
Cristiano Ronaldo and Harry Maguire were high-profile casualties of Ten Hag's recent shake-up but both are almost certain, barring injury, to get a start. Read more: Ten Hag gives update on Ronaldo's United future In goal, Martin Dubravka is likely to be handed his United debut.