Manchester City are aiming to avoid a third straight Premier League defeat for the first time in seven years when they host Brighton on Saturday, while Arsenal will provide a stiff test for resurgent Chelsea.
Four sides are in the running to top the table at some stage this weekend, starting with Liverpool when they take on Everton in the Merseyside derby.
AFP Sport looks at the pick of the action. Can City halt slide? City's defeats by Wolves and Arsenal before the international break were the first back-to-back losses in the league for Pep Guardiola's men since 2018.
You have to go back to the days of Manuel Pellegrini in early 2016 for the last time the champions lost three in a row, but Brighton pose a significant threat to City, who are on a run of 20 straight home wins in all competitions.