The following are some of the other contenders for the women's singles title at the U.S. Open, which begins on Sunday:
JESSICA PEGULA (UNITED STATES)
*World ranking: 4
Last year's U.S. Open runner-up will be eager to go one better but a shock French Open loss to wildcard Lois Boisson and a first-round Wimbledon exit has done little to help her confidence.
The 31-year-old has won two of her three titles this year on home soil, in Austin and Charleston, but since Wimbledon the American has struggled to produce her best form.
She lost to Leylah Fernandez in Washington, to Magda Linette in Cincinnati and to Anastasija Sevastova at the Canadian Open, where Pegula was a two-times defending champion.
She will be hoping to re-assert her authority in New York after failing to go beyond the fourth round in any of the year's first three majors.
MIRRA ANDREEVA (RUSSIA)
*World ranking: 5
The teenager became the youngest player to win a WTA 1000 title when she triumphed in Dubai aged 17 in February. She then backed it by toppling world number one Aryna Sabalenka in the Indian Wells final, having beaten Iga Swiatek en route.
While deep runs at Roland Garros and Wimbledon underscored her all-court credentials, it is on hardcourts that the Russian's game can do the most damage.
Andreeva's fitness will be under scrutiny at Flushing Meadows after she suffered an ankle injury during her Canadian Open third-round loss to McCartney Kessler. Unable to play in Cincinnati, she will be hoping her lack of match practice does not cut short her U.S. Open run.
MADISON KEYS (UNITED STATES)
*World ranking: 6
The Australian Open champion and 2017 U.S. Open runner-up proved that she has the temperament to win on the big stage after beating Sabalenka at Melbourne
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