Wales bring the curtain down on the rugby calendar as they finish with the hardest possible task against the world champion Springboks.
Steve Tandy is without 13 players for the out-of-window Test, while South Africa are also missing several top stars. The visitors have, though, named a formidable side led by captain Siya Kolisi.
As for Wales, wing Elis Mee comes straight into the starting team after his call-up this week, while Joe Roberts starts in the centre. There are also two new second rows in the shape of Ben Carter and Rhys Davies. The Wales matchday squad shows 14 changes from the one that lost to New Zealand.
The match kicks off at 3.10pm and is being shown live on TNT Sports. Welsh language commentary is available on S4C. You can follow live updates below.
Wales: Murray; Mee, Roberts, Hawkins, Dyer; Edwards, Hardy; G Thomas, D Lake (capt), Assiratti, Carter, R Davies, Plumtree, Mann, Wainwright.
Replacements: Coghlan, Southworth, Coleman, Ratti, Morse, Morgan-Williams, Sheedy, B Thomas.
South Africa: D Willemse; Hooker, De Allende, Esterhuizen, Moodie; Feinberg-Mngomezulu, Van der Berg; Steenekamp, Grobbelaar, Louw, Kleyn, Nortje, Kolisi (capt), Mostert, Wiese.
Replacements: Mbonambi, Porthen, Ntlabakanye, Etzebeth, Van Staden, Dixon, Smith, Reinach.
Read more on walesonline.co.uk