Munster's Tom Farrell and Leinster's Jimmy O'Brien have been called up to the Ireland side to face New Zealand in Chicago.
Farrell has been one of Munster's best players this season, and scored a try in their win over Leinster at Croke Park on Saturday.
Mack Hansen has been ruled out of the game with a foot injury he suffered when scoring a try for Connacht in their defeat to the Bulls on Friday.
Bundee Aki (hip) and Robbie Henshaw (groin) will continue to be assessed and will travel with the squad on Tuesday.
Munster forwards Brian Gleeson and Edwin Edogbo have been ruled out with respective concussion and elbow injuries.
Leinster's Tommy O'Brien is currently recovering from a back issue and Munster's Calvin Nash has already been ruled out of the game in Chicago with a shoulder injury.
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