Oct 07, 2025 - 09:47
By espn.com

NFL Week 5: Biggest questions, takeaways for every game - ESPN

Week 5 of the 2025 NFL season kicked off with an overtime showdown between the 49ers and Rams on Thursday night. San Francisco secured the 26-23 win after stopping Los Angeles running back Kyren Williams on fourth-and-1 at the 11-yard line.

Sunday's action began in London, as the Vikings salvaged their road trip thanks to a 12-yard touchdown in the fourth quarter that lifted Minnesota to a 21-17 win against the Browns. Later, the Texans got revenge from last Christmas against the Ravens, beating Baltimore by 34 points. The Saints grabbed their first victory of the season, topping the Giants 26-14. And the Eagles suffered their first loss, falling 21-17 to the Broncos.

The late-afternoon slate brought two competitive outings: The Bucs won a 38-35 thriller over the Seahawks, and the Titans stormed back late to beat the Cardinals 22-21.

In prime time, the Patriots — led by Drake Maye and Stefon Diggs — handed the Bills their first loss of the season.

To wrap up the week, the Jaguars delivered a big Monday night performance against the Chiefs, winning 31-28.

Our NFL Nation reporters reacted to all the action, answering lingering questions coming out of each game and detailing everything else you need to know for every team. Let's get to it.

Catch up on the action: Box score | Recap

Are the Jaguars a legit AFC contender? The Jacksonville's victory sent a message to the rest of the AFC: The Jaguars sure look like legitimate contenders. They got another turnover and big play from the defense — Devin Lloyd's 99-yard interception return for a TD — and QB Trevor Lawrence scored on a stumbling