NFL Week 1 injuries - Kupp ruled out; Kittle questionable - ESPN

The 2023 NFL season got started Thursday night at Arrowhead Stadium, home of the defending Super Bowl champion Kansas City Chiefs, and it didn't go so well for the home team.

The Chiefs were upset by the Detroit Lions 21-20 behind a defensive effort that held Andy Reid's high-powered offense to six second-half points.

Kansas City wasn't able to overcome the absences of tight end Travis Kelce (knee), who missed a game for the first time since his rookie season in 2013, and defensive tackle Chris Jones (contract dispute). Will other teams be able to compensate without key players? The Los Angeles Rams will be without wide receiver Cooper Kupp (hamstring), who missed eight games last season, and a couple of other teams will be without top receiving targets.

The news was better for the Cincinnati Bengals. When quarterback Joe Burrow suffered a calf injury at training camp in late July, there was fear of him missing regular-season action. Now, six weeks later, he's not only ready to start the opener, but he'll do so having signed a record-breaking contract extension.

Here are more injury updates from our NFL Nation reporters as we head toward Sunday's matchups:

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Injury: Hamstring

Coach Sean McVay ruled out Kupp for Sunday in Seattle, saying the Rams were going to make sure they didn't «rush» the wide receiver back from the injury. Kupp first injured a hamstring in a training camp practice on Aug. 1 and experienced a setback last week. McVay didn't rule out putting Kupp on injured reserve before Saturday, but he said the team wants to «give him a little bit of time» before it makes that decision.

— Sarah Barshop

Injury: Groin

Kittle is listed as questionable for Sunday against