Italy v England, Six Nations 2022 live: score and latest updates

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ITALY XV TO FACE ENGLAND: Padovani; Mori, Brex, Zanon, Ioane; Garbisi, Varney; Fischetti, Lucchesi, Ceccarelli; Cannone, Ruzza; Steyn; Lamaro (capt), Halafihi - Replacements: Faiva, Traore, Pasquali, Sisi, Negri, Pettinelli, Fusco, Marin.

ENGLAND XV TO FACE ITALY: Steward; Malins, Marchant, Slade, Nowell; Smith, Randall; Genge, George, Stuart, Ewels, Isiekwe, Itoje, Curry (capt), Dombrandt - Replacements: Cowan-Dickie, Marler, Sinckler, Chessum, Simmonds, Youngs, Ford, Daly

To Telegraph Sport's live blog of England's Six Nations match against Italy in Rome. Eddie Jones' side travel to the Eternal City on the back of a 20-17 defeat to Scotland in the opening round of fixtures. Defeat today is not an option for a side featuring six changes from the XV that lost in Edinburgh.

Here are five talking points ahead of the must-win match.

Ali v Liston III

The England coach has recalled one of sport's most iconic images to inspire the ruthlessness he wants to see from his team at the Stadio Olimpico. Muhammad Ali taunted Sonny Liston after knocking him down in the opening round of their second clash in 1965 and the picture of him stood above his stricken opponent is the metaphor Jones is using for what he wants to see from England on Sunday.

Healing the wounds of Murrayfield

A performance to "light up Rome" has been Jones' mantra for the week as England begin the task of rebuilding their Six Nations title challenge after falling to Scotland in round one. For the third successive year they have stumbled at the first hurdle and only an emphatic victory against the tournament's weakest