'I’m Pretty Sick Right Now': Sean McVay Takes Blame for Rams’ OT Loss to 49ers

Everything seemed to indicate the San Francisco 49ers were in for a long night when they traveled south on a short week without Brock Purdy, Nick Bosa, George Kittle and their top three wide receivers to face the surging Los Angeles Rams.

The Niners had a long Thursday night, all right — but after nearly 67 minutes featuring innumerable twists and turns, they headed home with an improbable victory that reasserted their dominance in their biggest NFC West rivalry.

"We talked about how tough we had to be for four quarters," quarterback Mac Jones said. "It came down to who was going to be the toughest team, and I think it was us."

Eddy Pineiro hit a 41-yard field goal in overtime before San Francisco stopped Kyren Williams on fourth down with 3:36 to play, and the short-handed 49ers hung on for a thrilling 26-23 victory.

Jones passed for 342 yards and two touchdowns while playing through a leg injury for the 49ers (4-1), who scored on their first two drives and led 20-7 late in the third quarter.

Los Angeles finally mounted a rally, but with help from several glaring Rams mistakes, the Niners hung on to win their first OT game since losing Super Bowl 58 in February 2024.

The frantic fourth quarter featured Piñeiro's tiebreaking 59-yard field goal with 2:52 left, Williams' subsequent goal-line fumble and Joshua Karty's tying 48-yard field goal for the Rams (3-2) with 2 seconds to play.

"They were unbelievable," 49ers coach Kyle Shanahan said of his players. "We talked about how long this game was going to be, how focused we had to be, how competitive we had to be for the entire time. Started out great, but it’s a good team. They tightened it up. Got real tight, then lost a number of dudes. We had to overcome losing two