Barcelona thrashed Sevilla 5-1 to re-establish a three-point lead at the top of LaLiga.
Robert Lewandowski's first-half brace, either side of a fine Pedri strike, put Barca in control and took the Poland striker's league tally for the season to 12.
Pablo Torre added a late double of his own, scoring either side of fellow substitute Stanis Idumbo's effort for Sevilla, as Barca again created daylight between themselves and second-placed Real Madrid.
Alexander Sorloth scored a second-half brace as Atletico Madrid came from behind to beat Leganes 3-1.
Leganes, sitting in 17th place after winning one game, led through Yvan Neyou's sublime finish, with Antoine Griezmann scoring between Sorloth's double.
Fourth-placed Villarreal slipped up at home to lowly Getafe as Mauro Arambarri's 87th-minute penalty cancelled out Santi Comesana's first-half effort in a 1-1 draw.
Vedat Muriqi's powerful header 15 minutes from time saw Real Mallorca beat Rayo Vallecano 1-0.
Napoli remain two points clear at the top of Serie A after winning 1-0 at Empoli.
On the day Scotland midfielder Billy Gilmour made his first league start, Napoli needed a Khvicha Kvaratskhelia penalty after 63 minutes to break down their resilient hosts.
Inter Milan stayed in touch with a hard-fought 1-0 victory at Roma.
Both sides struck the woodwork before Lautaro Martinez pounced on a Zeki Celik mistake on the hour to thump home his fourth goal in as many games.
Fifth-placed Fiorentina scored six goals in an away Serie A match for the first time since October 1966 as 10-man Lecce were torn apart.
Danilo Cataldi and Andrea Colpani both scored twice in a 6-0 win and Lucas Beltran and Fabiano Parisi were also on target.
Lecce were 2-0 down when Antonino Gallo was sent off just
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