College football Week 2 odds, moneyline, spreads and totals - ESPN

There is only one matchup between two ranked teams in Week 2, as No. 15 Michigan head to Norman for a showdown with No. 18 Oklahoma. Michigan defeated New Mexico 34-17 in Ann Arbor, while Oklahoma routed Illinois State 35-3 as QB John Mateer threw for 392 yards and Keontez Lewis hauled in two touchdowns.

Only four conferences — the Big Ten, ACC, Big 12 and SEC — as well as independent Notre Dame, are represented in this week's poll, making this the second time in 55 years that four or fewer conferences are represented, according to ESPN Research.

Make one pick each week and play for the $25,000 Grand Prize!

The action starts Saturday at noon ET on ABC with San Jose State Spartans taking on Arch Manning and No. 7 Texas Longhorns in Austin. Here's where you can find where to watch every game.

Here are the available betting lines for all Week 2 games featuring Top 25 teams.

See more: Michigan-Oklahoma betting tips |Heisman betting

All times Eastern. For latest lines, go to ESPN BET

Heather Dinich explains why LSU is currently the most complete team in the SEC, but notes that the conference remains wide open.

Florida International at No. 2 Penn State -42.5
Saturday, Noon, BTN

Records: Florida International 2-0, 0-0 vs. AP teams; Penn State 1-0, 0-0 vs. AP teams
Opening Line: Penn State -42.5, O/U 53.5
Money line: Off
Over/Under: 53.5 (O -110, U 110)

FPI Projection Penn State by 33.1 points, 98% probability to win game

San José State at No. 7 Texas -37.5
Saturday, Noon, ABC

Records: San José State 0-1, 0-0 vs. AP teams; Texas 0-1, 0-1 vs. AP teams
Opening Line: Texas -37.5, O/U 53.5
Money line: Off
Over/Under: 53.5 (O -110, U 110)

FPI Projection Texas by 37 points, 99% probability to win game

No. 11 Illinois -2.5 at Duke
Sa