College Football Week 10 Picks, Preview: What to Expect in PSU-OSU, More

The 2025 college football season is nearing the home stretch, and there's still a lot to be determined when it comes to the playoff race.

In one of the episodes of my podcast, "The Joel Klatt Show," this week, I predicted what the 12-team College Football Playoff field will look like. Saturday could help determine the field, as there are a few teams playing for their CFP lives against ranked opponents this weekend. It's also the last slew of games before the first CFP rankings of the season. 

As we preview what will happen in Week 10, I'll be in Columbus for another edition of the classic matchup between Penn State and Ohio State. 

Now, let's make some picks!

We all thought this game was going to be massive entering the year — maybe a top-five matchup or even a battle between Nos. 1 and 2. Alas, it isn’t. Penn State went cold, fired head coach James Franklin and is entering "The Shoe" on a four-game losing streak. Never thought I’d see that with Penn State. Meanwhile, Ohio State is undefeated and No. 1 by a wide margin in the AP poll. The Buckeyes have been the most dominant and complete team this season. 

That said, Penn State is going to come into this game with nothing to lose. Fake kicks, trick plays and dialing up on defense might all be in play. I think this is a kitchen sink game for the Nittany Lions because … why not? They’re not in the running for the Big Ten title game or a CFP berth, but they're still playing for pride. Let’s not be buried under a rock here and not at least acknowledge that PSU still doesn’t have one of the most talented rosters in the country. The Nittany Lions shouldn’t have four losses, but they were all determined by a score, so they’re not a bad team.

Ethan Grunkemeyer will be at