Christian McCaffrey says 'I feel great' despite calf injury casting doubt over 49ers season opener

Colin Cowherd unveils his final NFL predictions heading into the season, with the Cincinnati Bengals, New England Patriots and Seattle Seahawks clinching Wild Card spots.

Christian McCaffrey’s availability is once again a big question mark for the San Francisco 49ers just days before their season opener against the Seattle Seahawks.

However, the running back himself doesn’t seem worried at all about whether he will play in Seattle on Sunday.

"I always plan to play," he told reporters, via ESPN. "I feel great about where I'm at. Unfortunately, when you have the injury history that I have, sometimes when you don't practice, things get blown out of proportion. But like I said, I feel great."

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Christian McCaffrey #23 of the San Francisco 49ers warms up prior to the NFL Preseason 2025 game against the Las Vegas Raiders at Allegiant Stadium on Aug. 16, 2025 in Las Vegas, Nevada.  (Ian Maule/Getty Images)

McCaffrey was deemed questionable to play in the 49ers’ injury report on Friday due to a calf issue. He was listed as a limited participant at practice on Thursday, and after not practicing on Friday, fans are wondering if this is déjà vu after last year’s injury debacle.

McCaffrey was listed as questionable entering Week 1 last season, and he insisted he was fine and ready to play against the New York Jets. But he instead landed on injured reserve as his calf tightness turned out to be bilateral Achilles tendinitis. McCaffrey ended up playing just four games last season.

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So, as 49ers fans see a calf ailment again on the injury report, there is some skepticism leading into