Munster will be without Peter O'Mahony once again for Sunday's Investec Champions Cup Pool 3 meeting with Exeter at Sandy Park.
The flanker hasn't recovered in time from a shoulder injury which he suffered in his side's BKT URC win against the Stormers last month.
Head coach Graham Rowntree has made six changes from their disappointing 17-17 draw against Bayonne last week, as they look to get their pool campaign back on track against the 2020 champions.
There's an interesting selection in the forwards where Gavin Coombes moves in from number 8 to the second row, while Tom Ahern is retained at blindside flanker for the fourth game in a row.
Jack O'Donoghue comes into the starting team at the base of the scrum, with hooker Diarmuid Barron and tighthead prop Stephen Archer the other changes in the pack.
Jeremy Loughman, Tadhg Beirne, and John Hodnett retain their places in the side, with Beirne captaining the province for the second game in a row.
In the backline, Craig Casey is preferred to Conor Murray at scrum-half and links up with Jack Crowley in the half-backs.
Antoine Frisch returns to the centre in place of Rory Scannell where he joins Alex Nankivell, while Shane Daly is fit to start at full-back, allowing Calvin Nash move back to the wing.
Seán O'Brien has come through his return to play protocols and starts on the left wing.
Munster: Shane Daly; Calvin Nash, Antoine Frisch, Alex Nankivell, Seán O'Brien; Jack Crowley, Craig Casey; Jeremy Loughman, Diarmuid Barron, Stephen Archer; Gavin Coombes, Tadhg Beirne (C); Tom Ahern, John Hodnett, Jack O’Donoghue.
Replacements: Eoghan Clarke, Josh Wycherley, Oli Jager, Brian Gleeson, Alex Kendellen, Conor Murray, Rory Scannell, Ben O’Connor.
The Leinster team to face Sale Sharks sees
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