49ers pull away from Cardinals behind Christian McCaffrey's scoring onslaught

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Christian McCaffrey scored a career-high four touchdowns and the San Francisco 49ers won their 14th straight regular season game, beating the Arizona Cardinals 35-16 on Sunday.

McCaffrey gained 177 yards from scrimmage, scoring on three runs and one catch to help the 49ers get off to their fifth 4-0 start in franchise history. He also broke Jerry Rice's franchise record by scoring a TD in his 13th straight game, including the playoffs.

Brock Purdy went 20 for 21 for 283 yards with a TD run and pass, setting a 49ers franchise record for completion percentage in a game. He won for the ninth time in nine career regular season starts, leading the 49ers to their fourth straight game with at least 30 points to open the season.

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Joshua Dobbs threw for 265 yards and two touchdowns to Michael Wilson for the Cardinals (1-3), who were unable to follow up last week's upset at home against Dallas with another win against an NFC powerhouse.

Arizona had no answer to slow down McCaffrey, who became the first player in nine years to start the season with four straight games with at least 100 yards from scrimmage and a TD. He finished with 106 yards on the ground to go with seven catches for 71 yards.

San Francisco 49ers running back Christian McCaffrey (23) celebrates after scoring against the Arizona Cardinals during the second half of an NFL football game in Santa Clara, Calif., Sunday, Oct. 1, 2023.  (AP Photo/Godofredo A. Vásquez)

McCaffrey scored on a 1-yard run on the opening drive, took a lateral and hurdled a defender for an 18-yard run on the second drive and caught a 6-yard TD pass in the