49ers-Giants Thursday Night: NFL betting odds, picks, tips - ESPN

An undermanned New York Giants offense that will be without Saquon Barkley faces the San Francisco 49ers (-10, 44.5) at Levi's Stadium on Thursday night.

The 49ers moved to 2-0 with a road win over the Rams in Week 2, while the Giants rallied from 21 points down to knock off the Cardinals.

So what can we expect from a betting standpoint for Thursday night's game?

Betting analysts Tyler Fulghum, Erin Dolan, Eric Moody andSeth Walderare here to provide their thoughts.

Note: Lines from Caesars Sportsbook unless otherwise indicated.

Fulghum: Very little of it will carry over due to the short week and travel to Santa Clara to play what I believe is the best team in the NFL. It was an incredible comeback by the Giants (which salvaged my Eliminator entry), but Arizona is maybe the worst team in the league. To even need that comeback is somewhat embarrassing for the Giants. San Francisco is far more similar to the Dallas team that New York played in Week 1, and we all know what happened there. This could be a sobering experience for the Giants after their incredible Week 2 win.

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Moody: Those emotions will carry over to the next game because a comeback like that helps build team culture, chemistry, and mental toughness. That said, the 49ers are not the Cardinals, it's a short week, Barkley will not play and the Giants are on the road. San Francisco undoubtedly has one of the best defenses in the league and is capable of stopping the run. They also have a ferocious pass rush, and bettors haven't forgotten