2025 NFL MVP Odds, Race: Josh Allen Leads; Star QBs in Pursuit

NFL Week 5 is in the books, and it's already clear that this year's MVP race is gonna be a barnburner.

Let's take a look at the oddsboard at DraftKings Sportsbook as of Oct. 7, as well as what to know about each contender.

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2025-26 NFL MVP odds

Josh Allen , QB, Bills : +150

What to know: Allen is the reigning MVP, and through five weeks (4-1), he has nine passing TDs, three rushing TDs and two interceptions. However, he has had a pick in each of the last two weeks, and his Bills suffered their first loss of the season in Week 5 — at home to division rival New England. 

Patrick Mahomes , QB, Chiefs : +370 

What to know: Mahomes is the only two-time regular-season MVP in the top eight, and on the season, he has eight TDs and two picks, one of which he threw in the Chiefs' Monday night loss to Jacksonville. K.C. is now 2-3 on the season, and it will face the 4-1 Lions in Week 6. 

Justin Herbert , QB, Chargers : +1000 

What to know: After wins over all three division opponents, the Chargers suffered their first loss of the season in Week 4 at the Giants, and followed that up with a Week 5 loss at home to the Commanders. In that defeat, Herbert threw for fewer than 200 yards for the first time this season, and he threw at least one pick for the third straight week.

Baker Mayfield , QB, Buccaneers : +1100

What to know: The Bucs are 4-1, and Mayfield is cooking. He has 10 TDs and one pick on the season, and three of those four Tampa wins have come on the road, including a Week 5 win at Seattle. In that win over the