2025 NFL, CFB Odds: Best Bets for Seahawks-Panthers, Indiana-Alabama

Now that we’re all blissfully overfed and overserved from the holidays, wearing sweatpants around the house all weekend, let’s make some bets.

What a life.

There are five football games I’ve bet, including a College Football Playoff wager, since those games are Wednesday and Thursday.

Remember, this isn’t the place for "locks" or five-team parlays. These are the games I love the most.

Let’s go to work.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports .

2025 record: (34-47-6, -17.4 units)

Seahawks (-7, O/U 42.5) @ Panthers

The Seahawks hype machine is flying at full speed after last Thursday night’s overtime win over the rival L.A. Rams. Now everybody understands Seattle is good enough to string some playoff victories together. I still don’t think they’re seven points better than Carolina in Charlotte. We’ll see. I love this Bryce Young-Tet McMillan combo and do think the Panthers battle here.

PICK: Panthers (+7) to lose by fewer than 7 points or win outright

Steelers (-3, O/U 34) @ Browns

Wise guys bet Cleveland +4 and +3.5 earlier this week when pessimistic news surfaced about T.J. Watt’s status for Pittsburgh. Watt will officially be sidelined again, and the market is now painted 3 with one of the lowest totals all season. If that’s not a Browns’ script, nothing is. It’s also worth noting that if Baltimore loses Saturday night, this game means nothing for Pittsburgh.

PICK: Browns (+3) to lose by fewer than 3 points or win outright

LSU vs. Houston (-1.5, O/U 42)

First off, this is a glorified home game for Houston at NRG Stadium. The Cougars are very healthy and