2025 College Football odds: Lines, spreads for marquee Week 1 matchups

The 2024 college football season ended with Ohio State defeating Notre Dame to win the Playoff in its inaugural year of the 12-team format.

And while the Buckeyes are still on cloud nine, it's already time for fans to look ahead to next season.

With that in mind, let's dive into the odds for several marquee matchups on tap for Week 1 of the 2025 college football season, courtesy of FanDuel as of Jan. 22.

(All times, TV TBD)

SAT, AUG. 30

Texas @ Ohio State

Point spread: Ohio State -4.5 (Ohio State favored to win by more than 4.5 points, otherwise Texas covers)
Moneyline: Ohio State -176 favorite to win(bet $10 to win $15.68 total); Texas +146 underdog to win (bet $10 to win $24.60 total)
Total scoring Over/Under: 51.5 points scored by both teams combined

What to know: Two teams that ended this season ranked in the top five, with Ohio State at No. 1 after winning the national title, and Texas at No. 4 after falling to OSU in the CFP semis. Ohio State is favored to repeat as champions, with superstar wide receiver Jeremiah Smith back in the fold. Both teams figure to have new starting QBs, highlighted by Arch Manning taking over the reins for Texas. 

Notre Dame @ Miami (FL)

Point spread: Notre Dame -2.5 (Notre Dame favored to win by more than 2.5 points, otherwise Miami covers)
Moneyline: Notre Dame -128 favorite to win(bet $10 to win $17.81 total); Miami +106 underdog to win (bet $10 to win $20.60 total)
Total scoring Over/Under: 53.5 points scored by both teams combined

What to know: Notre Dame finished this season ranked No. 2 and Miami landed at No. 18. The Fighting Irish will return a good chunk of its roster, and while the Hurricanes are losing projected No. 1 pick Cam Ward, they are replacing him with former