Before the first whistle of the 2025 college football season blows and play begins, the betting market is already moving. Week 1 lines are live at ESPN BET with season win totals and futures shaping up. Each team in the preseason AP top 25 poll has a story, whether it's a rebuild, a reload or a revenge tour.
I've combed through the markets and picked one betting angle for every Top 25 ranked team, including win totals, long shots and even some bets for Week 1. There is plenty of head-to-head matchups, stability edges and fade-worthy hype. Here are 25 bets to consider before the college football chaos begins.
All odds are accurate as of time stamp. All times Eastern. For the latest odds go to ESPN BET.
The bet: Texas to miss the playoff (+220)
Texas is currently the favorite to win the national championship at ESPN BET, but this feels more like hype than substance. If the Longhorns drop two road games at Ohio State and Georgia, they have zero margin for error the rest of the way. And winning games against teams like Florida, Kentucky and Texas A&M isn't guaranteed with such a young roster. All three games are tricky spots for Texas, especially late in the year. Even with a strong recruiting class, asking Arch Manning to go nearly perfect through that stretch is a lot. That's why Texas going 10-2 feels like the smart bet. Taking the Longhorns to miss the playoff has real value.
The bet: Penn State over 10.5 wins (+130)
Penn State is built for another deep playoff run this year. Drew Allar enters his third season as the Nittany Lions' starter with continuity around him. Top backs Kaytron Allen and Nicholas Singleton return, and while Tyler Warren is gone, the receiving room stays intact with Harrison Wallace III and Omari
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