2025-26 March Madness Odds: 8 Best Bets for Men's Sweet 16

Only 16 teams remain in the NCAA Tournament, as play resumes Thursday evening. 

After an opening weekend that saw most of the favorites advance, a lack of upsets sets the table for what promises to be some incredible matchups going forward. 

By Sunday night, we will have a Final Four set, so let’s take a look at each game, and which teams might win their way to Indianapolis.

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No. 11 Texas vs. No. 2 Purdue

Sean Miller’s Texas squad went from the bubble to the First Four to the Sweet 16 after banking three Tournament wins. The Longhorns face a Purdue team that seems to be peaking at the right time after a disappointing regular season. I’m betting on a closer game than expected here. Both teams play at a relatively slow pace, and Texas is elite at getting to the foul line (eighth in the country averaging 26 free-throw attempts per game). Purdue beat Miami by 10 in the last round, but that was a four-point game with under a minute left before Purdue pulled away with late free throws. I like Texas to hang around.

PICK: Texas (+7.5) to lose by fewer than 7.5 points or win outright

No. 9 Iowa vs. No. 4 Nebraska

Part of Black Friday tradition involves these teams squaring off on the gridiron, but now they meet on the hardwood for a trip to the Elite Eight on the line. Iowa is as close to a Cinderella as we have in this Tournament, after the Hawkeyes got the upset win over double-digit favorite Florida. I was hoping to get Iowa plus a handful of points again, but with a line of 1.5, I’m looking at the total — particularly the Under of