2024 NFL Week 16 betting - Denver Broncos at Los Angeles Chargers picks, odds, lines - ESPN

Week 16 of the NFL season gets going with a key AFC West clash between the Denver Broncos (9-5) and Los Angeles Chargers (8-6) on «Thursday Night Football.»

The division rivals head into the week holding the final two spots in the AFC playoff race. The Broncos are -1200 to make the postseason, while the Chargers sit at -1000.

Denver will be looking for its fifth straight win after knocking off the Indianapolis Colts 31-13 last Sunday. Los Angeles is coming off its second straight loss, a 40-17 drubbing at home vs. the Tampa Bay Buccaneers. The Chargers won the first meeting, 23-16, in Denver in Week 6.

Action from SoFi Stadium gets underway at 8:15 p.m. ET on Prime Video.

Odds current as of publish time, courtesy of ESPN BET

Spread: Chargers -3 (Opened Chargers -3)
Moneyline: Chargers -150, Broncos +130
Over/Under: 42.5 (Opened 42.5)

First-half spread: Chargers -0.5 (-115), Broncos +0.5 (-105)
Broncos total points: 19.5 (Over -125/Under -105)
Chargers total points: 21.5 (Over -115/Under -115)

Matchup predictor (according to ESPN Analytics): Chargers 57.7% chance to win

Justin Herbert total passing yards: 224.5 (Over -135/Under +105)
Herbert total passing TDs: 1.5 (Over +110/Under -145)
Bo Nix total passing yards: 224.5 (Over +100/Under -130)
Nix total passing TDs: 1.5 (Over +145/Under -190)

Gus Edwards total rushing yards: 34.5 (Over -115/Under -115)
Nix total rushing yards: 19.5 (Over -135/Under +105)
Kimani Vidal total rushing yards: 29.5 (Over +105/Under -135)

Ladd McConkey total receiving yards: 69.5 (Over +105/Under -135)
Courtland Sutton total receiving yards: 69.5 (Over +105/Under -135)
Quentin Johnston total receiving yards: 39.5 (Over -130/Under +100)
Stone Smartt total receiving yards: 39.5 (Over +105/Under -135)
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