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Last season's Derby and King George VI And Queen Elizabeth Stakes hero Adayar will miss the Coral-Eclipse at Sandown and instead head straight to Ascot to defend his all-aged middle-distance crown.
Coronation Cup winner Hukum has fractured a hind leg and will miss the remainder of the season.
Vadeni produced a dominant display to provide trainer Jean-Claude Rouget with a fifth victory in the Qatar Prix du Jockey Club at Chantilly.
Desert Crown ran out a decisive winner of the Cazoo Derby (In Memory Of Lester Piggott) at Epsom to give trainer Michael Stoute a sixth success in the premier Classic.
Tuesday was announced the winner of the Cazoo Oaks after a photo finish was required to divide the filly and the second-placed Emily Upjohn.
It was a case of sweet revenge for Jim Crowley as Hukum stormed to an impressive success in the Dahlbury Coronation Cup at Epsom.
Emily Upjohn and Nashwa give John Gosden a formidable hand in his bid for a fourth victory in the Cazoo Oaks at Epsom on Friday.
Willie Muir is confident he has Pyledriver exactly where he wants him as he bids to follow up last year's success in the DahlBury Coronation Cup at Epsom on Friday.