Dak Prescott threw for four touchdown passes as the Dallas Cowboys eased to a 45-10 Thanksgiving victory over the Washington Commanders.Tony Pollard added a seven-yard touchdown run, while DaRon Bland rounded things off with a 63-yard interception return for a score – his fifth of the season to set an NFL record.The win lifts the Cowboys to 9-3 and stretched their home-winning run to 13 matches.For the Commanders, who have lost eight of their last 10 matches, Sam Howell threw for 300 yards and ran for a touchdown.The Green Bay Packers beat NFC North leaders the Detroit Lions 29-22.Jordan Love connected with Christian Watson from 53 yards on the first play of the game and ended with three touchdown passes.Opposite number Jared Goff struggled against the Packers defence, fumbling three times – one of which was returned for a touchdown by Jonathan Owens.The San Francisco 49ers strengthened their position at the top of the NFC West, moving two games clear with a 31-17 win over the nearest challenger, the Seattle Seahawks.Much of the damage was done in the first half as the 49ers took a 24-3 interval lead on the back of three running touchdowns, two of them from Christian McCaffrey, who rushed for 114 yards before half-time.The Seahawks cut the gap to 14 points when Jordyn Brooks returned an interception from Brock Purdy for a touchdown, and Jason Myers landed a field goal.But Purdy sealed the 49ers third straight win as he found Brandon Aiyuk from 28 yards for a touchdown midway through the fourth quarter.