Ciro Immobile climbed off the bench to hit two late Lazio goals and send Celtic crashing out of Europe after a 2-0 defeat in Rome.
The Hoops were still well in the hunt for the victory that would have kept their hopes alive until Immobile netted twice in three minutes and sicken them in the Stadio Olimpico.
It means Celtic's Euro hopes are over for another season with a Group E game to spare against Feyenoord in their final fixture.
A miserable night for the visitors was completed when they were awarded a penalty in injury time - only for it to be overturned after a VAR check.
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