Williams sisters withdraw from Wimbledon doubles after Serena suffers knee injury

Serena Williams called the anti-doping process 'unprofessional' ahead of her return at Wimbledon. (This video contains AI-assisted content.)

The Williams sisters' return to competitive tennis as a duo was over before it started.

In their first Grand Slam doubles competition together in nearly four years, Serena, 44, and Venus, 46, were forced to withdraw from Wimbledon after Serena injured a knee.

Serena was injured during her singles return earlier in the week in a three-set loss.

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Serena Williams and Venus Williams of the United States during their women's doubles match at Arthur Ashe Stadium against Lucie Hradecká and Linda Nosková of the Czech Republic during the U.S. Open at the USTA National Tennis Centre Sept. 1, 2022 in Flushing, Queens, New York City. (Tim Clayton/Corbis via Getty Images)

"I’m heartbroken to have to withdraw from doubles. Coming back to compete again has been a gift, and the opportunity to play alongside @venuswilliams once more meant the world to me. I did everything I could but unfortunately my knee just isn’t ready to compete," Serena said in an Instagram post.

The post included images of four syringes that Serena said "shows the fluid they drained from my knee after my singles match." An accompanying video showed her walking with strapping up and down her right leg and what appeared to be one of her daughters holding a cane for her.

However, with the U.S. Open approaching, Serena indicated she could play again somewhere else soon.

"All I can say," Serena said, "is stay tuned to a city near you."

Serena Williams, left, meets her sister Venus Williams after their match during the third round of the U.S. Open tennis tournament, in Flushing,