Wales v England LIVE: Start time, team news and score updates

Wales look to finally end their 16-match losing run in the most dramatic way imaginable as they face Six Nations title-chasing England in Cardiff.

Matt Sherratt takes charge for the last time before returning to Cardiff, and the interim boss has made two changes from the side that lost to Scotland. Aaron Wainwright starts in the back row as he aims to secure a Lions spot, while Joe Roberts comes in on the wing.

England have recalled Marcus Smith at full-back, while Tom Roebuck starts on the wing and Tommy Freeman moves to centre. Steve Borthwick's side realistically need to win with a bonus point and hope France slip up against Scotland. Victory for Wales, or even a losing bonus point, could well see them avoid he Wooden Spoon.

The game kicks off at 4.45pm and you can follow live updates before, during and after the match below.

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Wales XV: Blair Murray; Ellis Mee, Max Llewellyn, Ben Thomas, Joe Roberts; Gareth Anscombe, Tomos Williams; Nicky Smith, Elliot Dee, WillGriff John, Will Rowlands, Dafydd Jenkins, Aaron Wainwright, Jac Morgan (captain), Taulupe Faletau.

Replacements: Dewi Lake, Gareth Thomas, Keiron Assiratti, Teddy Williams, Tommy Reffell, Rhodri Williams, Jarrod Evans, Nick Tompkins.

England XV: M Smith; Roebuck, Freeman, Dingwall, Daly; F Smith, Mitchell; Genge, Cowan-Dickie, Stuart, Itoje (capt), Chessum, T Curry, B Curry, Earl.

Replacements: George, Baxter, Heyes, Hill, Cunningham-South, Pollock, van Poortvliet, Ford.