NFL Round-up: Hopkins downs Niners and Belichick waits for 300th win

Dustin Hopkins kicked a go-ahead, 29-yard field goal with 1:40 left in the game and the host Cleveland Browns spoiled the San Francisco 49ers' chance at a perfect season with a 19-17 victory on Sunday afternoon.

Jake Moody had a golden opportunity to allow San Francisco (5-1) to escape with a win, but he missed a 41-yard field-goal attempt wide right with six seconds to play.

Jordan Mason had put the 49ers ahead 17-13 when he rushed for an 8-yardtouchdown with 10:58 remaining. Hopkins made a 50-yard field goal just over seven minutes later to pull Cleveland (3-2) within one, and the Browns' defence followed by forcing a three-and-out to set up the game-winning drive.

The 49ers lost star running back Christian McCaffrey (oblique) and wide receiver Deebo Samuel (shoulder) to injuries. Without those weapons, Brock Purdy struggled, completing just 12 of 27 passes for 125 yards with a touchdown and an interception. He took his first regular-season loss as a starter, falling to 10-1.

Cleveland quarterback PJ Walker had 192 yards and two interceptions on 18-for-34 passing while starting in place of Deshaun Watson (shoulder).

Tony Adams picked off Jalen Hurts on the first play after the two-minute warning and Breece Hall scored from eight yards out on the next play the for New York Jets, who overcame an 11-point deficit to stun the previously unbeaten Philadelphia Eagles 20-14 in East Rutherford, New Jersey.

The win was the Jets' first-ever against the Eagles, who won the first 12 meetings between the franchises. Zach Wilson completed a two-point conversion pass to Randall Cobb following Hall's TD. Wilson threw for 186 yards on19-for-33 passing.

Eagles quarterback Jalen Hurts had 280 yards passing -- including 131 to AJ Brown -- and