Jamie George to miss Ireland game as England injuries mount

England have been hit by the loss of vice-captain Jamie George for their Guinness Six Nations opener against Ireland on 1 February, with Alex Mitchell also a doubt for the Dublin clash.

Hooker George suffered a hamstring injury in Saracens' Investec Champions Cup defeat by Castres on Sunday and will miss the start of the tournament, the Rugby Football Union has confirmed.

Northampton scrum-half Mitchell sustained a knee problem against Munster on Saturday but could yet feature against Ireland after being taken to the squad’s pre-Championship training camp in Girona to continue his rehabilitation.

An attritional weekend of European action has also seen Northampton lock Alex Coles, Leicester scrum-half Jack van Poortvliet and Harlequins number eight Alex Dombrandt ruled out of contention for the Aviva Stadium clash.

Watch Dragons v Munster in the URC on Saturday from 7.15pm on RTÉ2 and RTÉ Player; Watch Ulster v Zebre in the URC on Sunday from 5pm on RTÉ2 and RTÉ Player

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